Sentence examples for a common tumor defect from inspiring English sources

Similarly, increased expression of the homeobox transcription factor Six1 is a common tumor defect that arises in the majority of patients with metastatic ovarian or breast cancer, is associated with poor clinical outcome in multiple tumor types [20] and causes inhibition of TRAIL but not FasL-induced apoptosis [21].

Neurofibromatosis type 1 (NF1) is a common tumor predisposition syndrome in which glioma is one of the prevalent tumors.

This was exemplified in a study by Fine and colleagues [ 77], revealing that overexpression of uncoupling protein (UCP) 2, a common defect in tumor mitochondria, rendered these cells vulnerable to treatment with the ketone body acetoacetate [ 77].

Still, loss of p53 function correlates with multidrug resistance in many tumor types [ 11] and the observation that this is a common defect in human tumors has spurred an active search for strategies aimed at directly activating cell death pathways downstream of p53.

Hypospadias is a common birth defect.

Neural tube defects (NTD) are a common birth defect, with both genetic and environmental contributions to their etiology.

Cleft palate (CP) is a common birth defect with an incidence of 1 1500 (1 1500

Holoprosencephaly (HPE) is a common congenital defect that results from failed or incomplete forebrain cleavage.

1938: Surgeons repair an undeveloped fetal vessel, a common defect.

And Romney shares a common Republican personality defect: he doesn't empathize with average Americans.

Congenital heart disease is a common inherited birth defect.