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Autozygosity mapping in the eight affected animals revealed a common segment of extended homozygosity encompassing 1,023 kb (BTA 21: 70,550,045 - 71,573,501).
Although single-copy genes are predominant in this genome, the two ends of the smallest chromosome (chromosome I) share a common segment of ~ 37 kbp that encompasses the subtelomeric rDNA unit and covers a cluster of six genes [ 11].
In five of those regions located in scaffolds 1, 2, 3, 5, and 7, we identified a common segment of 200 bp with conserved sequence motifs defined by the regular expression shown in figure 1.
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The rectosigmoid is the most common segment of bowel involved.
Rectosigmoid is the most common segment of the bowel involved [ 15, 18, 36– 36].
In rare cases, the difference is located elsewhere, including in the common segment of both copies that could differ for only one residue.
The region between the two markers RM20562 and RM29572 for groups D and J shared common segment harboring of qTGW6.
Given an initial segment endpoint (starting from the first element of the list), this process involves searching for the final endpoint of a common line segment (among the subsequent elements of the list) that produces the highest segment strength above a threshold μ s.
In the accompanying web-tool, this is illustrated with both order statistics (length of maximum common segment) and parametric statistics (sum of lengths).
Autozygosity mapping within the distal region of BTA 21 revealed a common 1,023 kb segment of extended homozygosity in the eight affected animals (70,550,045 bp – 71,573,501 bp).
The common segment method has a long history of use in congenic inbred strains (Snell and Bunker 1965), but alternative methods for mapping have recently been proposed to be more rigorous.
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