Marked neovascularisation is a feature of malignant ascites, the most common dissemination route of advanced serous ovarian cancer, and several angiogenic markers, including VEGF, are highly overexpressed in ovarian cancer (Ueda et al, 2005).
Here, we review the current understanding of common dissemination pathways for tumors.
iTools provide the infrastructure for a common resource description and dissemination, manages the meta-data about these resources, and enables the investigation of resource interoperability.
Angiogenesis may also promote lymphatic dissemination, a common occurrence in breast carcinoma, by elevating tumour interstitial pressure.
This lack of confidence is not surprising; it has been cited as a common barrier to widespread dissemination and implementation (Hutchinson and Huberman, 1994; Henderson et al., 2011).
See related editorial by Gebauer, Tumour cell dissemination is a common phenomenon in breast cancer where isolated disseminated cells can be detected in up to 40% of patients at the time of primary diagnosis [ 1- 3].
Emerging evidence from studies on bone marrow suggests that tumor cell dissemination is a common event which starts at an early stage, and that disseminated cells may evolve at the ectopic site independently of the primary tumor [ 44, 45].
Subsequently, we establish a probabilistic model to theoretically analyze the tradeoff between timely temporal data update and requested data dissemination sharing a common communication resource, which provides a deeper insight of the proposed RTIS.
Because plasmid co-localization of QnrA and VEB-1 encoding genes has been reported repeatedly from scattered clonally-unrelated enterobacterial isolates, our objective was to use replicon typing to trace a possible dissemination of a common plasmid worldwide.
Third, because livestock products are a common source of salmonellosis, the dissemination of ciprofloxacin-resistant S. Typhimurium might have been facilitated by the use of fluoroquinolones in livestock production (2 ).
