Sentence examples for a committing step from inspiring English sources

This is a committing step in the folate pathway because HP is the first compound in the pathway used only for the biosynthesis of folate cofactors.

Rb, along with the CDK inhibitor p27, is also among the substrates of cyclin E/CDK2, which inactivates them by phosphorylation – a committing step for S-phase entry.

We identified, cloned and characterized a N. oceanica microsomal-like Δ12-desaturase (NoD12) mediating the committing step of LC-PUFA biosynthesis by converting oleic acid (18 1 n − 9) to linoleic acid (LA,18 2 n − 6).

MGAT1: committing step for synthesis of hybrid- and complex-type N-glycans.

This reaction is the first committing step in the pathway and catalyzed by Acetyl-CoA Carboxylase (ACCase).

Dihydroflavonol reductase (DFR) activity is the committing step for leucoanthocyanidin synthesis and proanthocyanidin, anthocyanidin and anthocyanin synthesis follows this step [ 50].

* Contigs representing full length genes Oxidative decarboxylation of pyruvate to acety-CoA by pyruvate dehydrogenase (PDH) is the first committing step in fatty acid biosynthesis.

The product of 4CL, p-coumaroyl-CoA, is the substrate of the enzyme chalcone synthase (CHS) [ 24], which carries out the committing step in flavonoid biosynthesis.

The committing step for taxol production was the conversion of GGPP to taxa-4 5 -11(12)-diene taxa-4 5 -11penoid biosynthesis pathway; however, genes involved in this reaction, as well as the following processes, were absent from our KEGG annotation.

53BP1 plays a central role in DSB repair as it contributes to NHEJ directed repair by acting as a scaffold for the accumulation of other proteins such as RIF1 35– 39 and PTIP 40 to inhibit end resection, the committing step of HR.

In addition, a series of genes encoding two enzymes of committing steps in the lipid biosynthesis pathway were examined as well: acetyl-CoA carboxylase (ACCase) and acyl-CoA, and diacylglycerol acyltransferase (DGAT), which catalyze the first and the final committed step in TAG biosynthesis, respectively.