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Each set (55730, 6475) was normalized and in the case of the comparison analysis, a combined expression set was generated.
A comparison analysis was also run in the same manner as above, with the "between array normalization" that also excluded probe sets that were not common to both chips, thereby generating a combined expression set.
A combined expression level of miR-21 and miR-126 accurately predicted CSS in two independent RCC cohorts and seems feasible for clinical application in assessing prognosis.
This finding inspired the suggestion of a combined expression of insulin dose and A1C, formulated as a specific definition of the IDAA1C = A1C (percent) + 4 × [insulin dose (units per kilogram per 24 h)].
Therefore, a combined expression analysis of several miRNAs may be a new diagnostic tool for the detection of DCM in Doberman Pinschers and should be further investigated in future studies.
Recent sequencing of additional T. gondii isolates identifies >620 K new SNPs, including ~11 K that intersect with expression profiling probes, yielding additional markers for genotyping studies, and further validating the utility of a combined expression profiling/genotyping array design.
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With the development of genomic technology, a promising approach to overcome limitations of the traditional method is to identify a set of genes as a genetic signature whose combined expression pattern is the uniquely characteristic of a given phenotype [ 3, 4].
In a Kaplan Meier analysis, the combined expression of both nERβ2 and cytoplasmic ERβ5 identified a group of patients with the shortest POM-free survival.
A study on the combined expression pattern of MUC4 and other molecules like E-cadherin or other mucins may provide more accuracy and specificity to use MUC4 as a diagnostic or prognostic marker for gastric cancer.
Gene signature, a group of genes whose combined expression pattern is uniquely characteristic of a biological phenotype or medical condition, can be a complement to classic prognostic factors to provide more accurate prognostic information [ 17].
The combined expression of an effector gene and a miRNA, which blocks translation of such antagonistic gene products, is a simple but elegant way to promote and support host gene functionality.
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