Sentence examples for a combined administration from inspiring English sources
While most studies have utilized single oligos either administered alone, or more recently in combination therapy with other drugs, some investigators have administered more than one oligo in a combined administration or have designed oligos which target multiple proteins (those which share mRNA sequence homology).
Although it has been experimentally confirmed that a combined administration of an anticoagulant with a lipid-lowering agent may help prevent steroid-associated ON [8], the ideal strategy would be simultaneously target both intravascular thrombosis and extravascular lipid deposition for preventing steroid-associated ON development [4].
The effect of a combined administration with cytostatic agents was now investigated.
Interestingly, a combined administration of TMZ and EEP led to 50% reduction of NF-κB nuclear translocation.
The effects of a combined administration of PME, FLX, or DES and d-serine on total duration of immobility in mice are shown in Figure 7(a).
Half of the patients with chronic HCV infection require antiviral treatment with a combined administration of Pegylated interferon (Peg-IFN) α and ribavirin [ 2, 3].
In comparison to AdVEGF-A-treated skeletal muscle, the combined administration of CX and VEGF-A resulted in dose-dependent blood vessel dilation and most notably an increased number of CD31/PECAM1-positive structures filling the lumen of the vessels (Table 2).
While both inhibitors had an effect as mono-agents, combined administration gave a stronger anti-tumour effect both in vitro and in xenografts models.
Aulinger et al. (abstracts 1,545 and 1,551) reported that although neither GLP-1 nor vildagliptin reduced food intake given separately in a rat feeding model, combined administration was effective.
We provide a demonstration that the combined administration of PYY3-36 GLP-17-36 GLP-17-36 GLP-17-36 humamidebjecto leads to similar reductions in subsequent energy intake and brain activity, as observed physiologically fasteding feeding.
However, none of these drugs achieved a satisfactory result and the combined administration of antithrombotic agents may provide a multipronged approach to the treatment of severe sepsis.
