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In most of the Phase III studies which provide full evaluation of efficacy (measured by HbA1c) and tolerability/safety, a wide spectrum of patients is recruited into different trials to evaluate the new medication in various treatment combinations (from drug-naïve patients to those on a combination that includes insulin) and against various comparators (placebo or different active controls).
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While approximately a quarter of patients receiving polypharmacy were prescribed a combination that included an FGA, the most frequently used combinations across all classes were combinations of SGAs.
Of the 17.2% of patients who remained on a polypharmacy regimen, 8.9% received a combination that included one of their index medications; 8.3% were switched to a polypharmacy regimen that included different medications.
An I was any combination of the three chips that contained two missing and an A or B or, any combination that included an A and B call from one of the three reps.
Whether the synergistic anti-tumor effect can be achieved using a drug combination that includes alphaviral vectors has been poorly investigated.
Since BayesA and BayesC0 estimate the phenotype by using a linear combination that includes the effects of each SNP across the genome, there is no guarantee that SNPs that are physically close to the QTL will dominate the prediction even in models in which the phenotype is determined by a single QTL.
For a GC-FID analysis, we suggest a five fiber combination that includes the 50/30 µm CAR-DVB-PDMS, 85 µm CAR-PDMS, 65 µm DVB-PDMS, 7 µm PDMS, and 60 µm PEG fibers.
(AP) — Oklahoma executed a convicted killer on Thursday using a drug combination that included a sedative common in euthanizing animals after a nationwide shortage of a main ingredient forced the state to tinker with its usual formula.
Similarly, rabbits anaesthetised with an anaesthetic combination that included a fentanyl component were also considered to have received an analgesic component in their anaesthetic [ 14].
In a first experiment, we manipulated the amount of rainfall in a factorial combination that included three levels of rainfall size (1, 5 and 15 mm), three soil covers: vegetated areas (VEG), biological soil crusts (BSC) and bare soil (BS) and two nearby sites: a natural grassland and a degraded grassland.
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