Complete genome annotation will likely be achieved through a combination of computer-based analysis of available genome sequences combined with direct experimental characterization of expressed regions of individual genomes.
Bacterial-specific inhibitors of an essential enzyme, thymidylate synthase (TS), were developed using a combination of computer-based screening followed by in-parallel synthetic elaboration and enzyme assay [Tondi et al. (1999) Chem. Biol. 6, 319 331].
As a first step in determining the possible role of rare autosomal deletions in our samples, we evaluated fluorescence intensities as presented by the Beadstudio program, using a combination of computer-based scanning and individual assessment by human observer.
In order to predict type and amount of defects created by keV ions under realistic implantation conditions, a combination of computer simulations based on the binary collision approximation (BCA) with classical molecular dynamics (MD) calculations is proposed.
The College Football Playoff replaced the first true, though imperfect, postseason football championship arrangement in the history of the NCAA's highest division: the Bowl Championship Series (BCS), a system instituted in 1998 that produced a national championship matchup based on a combination of computer rankings and polls.
Mr. Toporek said Walmart.com used a combination of computer tools and human adjustments.
Coding regions were assigned by a combination of computer prediction and similarity search.
RNA- and protein-encoding regions were assigned by a combination of computer prediction and similarity searches, as described previously.
Interviews were administered using a combination of computer-assisted personal interviewing and audio computer-assisted self-interviewing.
Essentially as a combination of computers and the human brains," he added.
DDM uses a combination of computer-aided design (CAD) and computer-aided manufacturing (CAM) as well as computer codes designed to interface with advanced 3-D additive manufacturing prototyping machines to produce a desired component (Yan and Gu 1996).
