Sentence examples for a collective cell from inspiring English sources

The Caenorhabditis elegans male gonad is shaped by a collective cell migration during larval development.

Being a part of such modules would require a coordinated evolution between their sequence and expression level to participate in a collective cell function.

This pathway further plays a fundamental role for the transition from a collective cell compound (epithelial) to individually moving (mesenchymal) cells in tumor development [ 558].

The developing male gonad is a collective cell migration consisting of a chain of passively migrating somatic and germ cells led by a migratory somatic cell, the linker cell (LC).

In Figure 1, a cancer with single cell invasion (panel A) is compared to a tumour with a collective-cell invasion pattern (panel B).

Here, in addition to showing a reduction in collective cell migration demonstrated in previous reports [ 19, 27, 28], JAM-A knockdown cells showed an approximate 50% reduction in individual cell motility in these matrix-specific transwell migration assays (P = 0.01), further underlining the important role of JAM-A in the regulation of breast cancer cell migration.

Recently, we have shown that in human squamous cell cancer, but also in an animal model of insulinoma, podoplanin is involved in a pathway of collective cell migration and invasion, which is independent from EMT (Wicki et al, 2006).

Their study showed that the expression of ECM-degrading proteases, such as MT1-MMP and MMP-2 at the leading edge of the cell aggregates are critical for cohort migration, a type of collective cell movement [22].

However, it is not clear how individual T cells coordinate their seemingly binary response they are either activated when they recognize a pathogen, or they are not activated into a response at the collective cell level that can be varied continuously over a wide range of values.

Recent experimental results have demonstrated that podoplanin, a small mucin-like protein, mediates a pathway leading to collective cell migration and invasion in vivo and in vitro (Wicki et al, 2006).

The experiments were designed to study the spatiotemporal dynamics of in vitro wound healing, particularly the effects of Hepatocyte Growth Factor/Scatter Factor (HGF/SF) [ 9, 10], as a model system to determine the effects of a growth factor on collective cell migration [ 2, 11].