The phrase "a cold challenge" is correct and usable in written English.
It can be used to describe a challenge that is presented in a detached or unemotional manner, often implying a sense of difficulty or harshness.
Example: "The team faced a cold challenge when they were tasked with completing the project under a tight deadline with minimal resources."
Alternatives: "a stark challenge" or "a harsh challenge".
Whenever you go into an environment that is less than your body temperature, you are exposed to a Cold Challenge.
After all, when every breath and step is a cold challenge, the sheer difficulty of survival trumps everything – which is why, further up, there are still some 200 bodies on the way to the mountain's summit that have not been hauled down, or even identified.
In contrast, Tfb2m was induced ∼10-fold in iWAT after a cold challenge, whereas its expression increased 2 3-fold in iBAT (Fig. 6B).
To assess the effects of lactogen resistance (PRLR deletion) on thermogenesis, we subjected newborn mice to a cold challenge and calculated their survival rates during the 400-min period, since alternative methods such as measurement of rectal temperature or indirect calorimetry could not be performed on newborn animals.
The diagnosis of RaP was confirmed if patients fulfilled LeRoy and Medsger's criteria [ 9] i.e., if a cold challenge induced bilateral, episodic bi- or triphasic (pallor followed by dusky blueness and/or redness) color changes of fingers.
The diagnosis of RP was confirmed if patients fulfilled LeRoy and Medsger's criteria [ 6]; that is, if a cold challenge induced bilateral, episodic biphasic or triphasic (pallor followed by dusky blueness and/or redness) color changes of fingers.
Using a placebo-controlled, double blind, randomised, crossover design, this study tested the hypotheses that acute beetroot supplementation would increase the rate of cutaneous rewarming following a local cold challenge and augment endothelium-dependent vasodilation in cold sensitive individuals.
Anakinra was also able to prevent cold-associated acute inflammation in patients with FCAS during an experimental cold challenge protocol to study the acute inflammatory mechanisms occurring after a general cold exposure in FCAS patients.
(A and B) The wildtype mice were subject to cold challenge.
This is a notable data point, since the challenge's origins are actually somewhat unclear, and have been attributed to a number of sources, including a "cold water challenge" that began in the Northern U.S., which is documented in more detail on KnowYourMeme.com.com
A-KO mice displayed decreased energy expenditure during 4 °C cold challenge.
