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If the difference is significant, then it is a strong indication for a cluster of sequencing errors.
For example, journalists have recently reported on a cluster of highly visible horrendous medical errors at prestigious teaching hospitals, including the Dana-Farber Cancer Institute in Boston, Memorial Sloan-Kettering Cancer Center in New York City and the University of Chicago Hospitals.
The cumulative MRs (after adding all corresponding errors within a cluster) of two clusters (namely clusters 1 and 5) are shown in Figure 9a,d, respectively.
That survey was prompted by a cluster of six cranial and spinal side errors that occurred in the neurosurgery department in Newcastle upon Tyne during the year 2006.
The results indicated that a 96% cutoff clustering of error-rich reads and a 97% cutoff clustering of filter-passed reads gave the worse results than a 96% cutoff clustering of filter-passed and selected filter-passed reads (Supplementary Fig. S3).
The encroachment of politics into the market process distorted commercial institutions, created an enormous cluster of entrepreneurial errors, and eroded people's trust in one another and in the very commercial institutions that had mediated their cooperation.
The communication systems and disk or tape memory can sometimes cause clusters of errors, namely burst errors.
The standard errors are adjusted for the potential clustering of errors at the regional level.
As shown below, these OTUs represent clusters of errors derived from very abundant organisms in the underlying population.
However non-uniform clusters of errors indicate that they are not independent and therefore redundant scans may not resolve the problem.
A clustering error of a split is counted as 1 if neither of the two cases is true, otherwise it is zero.
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