Since we observed that a cluster of data points showed a lower percentage of reciprocal expression among the WG duplicates in the ADA data set, we further explored the possibility that some organ types might greatly contribute to the reciprocal expression patterns among the WG duplicates.
It is noteworthy that there is a cluster of data points showing much lower percentages of reciprocal expression among the WG duplicates when more data points were subsampled (rectangular box in fig. 3 a ), suggesting that the inclusion of certain data points (i.e., certain organ types) might greatly contribute to the reciprocal expression patterns.
This statistical test was chosen because of a clustering of data points at zero.
In most cases, it is clear that there is a big cluster of data points on the left side of the y = x partition, meaning that kinases inhibited by the same compound are quite distant according to the sequence-based classification (distance 0.6 – 0.8), but rather close according to our fingerprint enrichment-based classification (distance 0 – 0.4).
Finally, the least-squares-support-vector-machine (LS-SVM) is used to build a submodel for each cluster of data points, and then all the sub-models are integrated into a model for the whole data set.
For both parameters, data from Mk-AK aligned with the cluster of data points formed by the other anti-Nogo-A antibody-treated monkeys (red squares), largely separated from the cluster of data points formed by the control antibody-treated monkeys (blue circles).
The reason why the two patients have the same correlation value, although there appears to be more variation in ALL2, is that the cluster of data points in the upper right corner has a major effect on the correlation.
This is in agreement with the result on the Day plot (Fig. 10a) that define cluster of data points of limited Mrs/Ms (0.21 0.25) and Bcr/Bc (2.3 2.6), falling in the medial leftward side of the PSD region, and close to the theoretical curve 3 for a mixture of single-domain (SD) and multi-domain (MD) particles derived by Dunlop (2002a, b).
Δ Tsk increased with FFMI in both male and female participants, but the female cluster of data points are situated to the left on the graph, indicating that, for a given FFMI, females cooled more than males.
There was an indication that, within the HG broccoli arm, there was less variability among individuals after the intervention than before because of a greater clustering of data points.
A correlation between the variables results in the clustering of data points along a line.
