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Even though the average differences between categories are small, there is a clear cut negative trend (Mann-Whitney U-test, P < 0.001; Figure 3A).
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The Median split rendered a clear cut between patients concerning negative symptoms, since the SANS global score in the low score group ranged from 0 to 16 and in the high score group from 24 to 74.
This value, indeed, represented a clear cut off concentration which was able to induce apoptosis only in the negative dominants (PCMT antisense or mutants), according to the markers so far employed.
"We believe we have a clear cut case.
Louis' story has a clear cut progression.
Alternative approaches to get round the need for a clear cut-off between positive and negative samples could be quantitative RT-PCR or the use of a combination of several markers so as to attain statistical significance.
This is despite the fact that clear-cut negative outcomes can be tremendously informative, telling us which potential interventions don't work or which suspected phenomena don't actually exist.
The matter of lungs are a little more clear cut.
Recent data provide no clear cut evidence of a link between PD risk and alcohol consumption with both positive and negative results.
The current biopsy shows that there is clear cut morphologic progression to a lymphomatous pattern with a striking tumefactive effacing growth of malignant lymphocytes in the superficial dermis predominated by large transformed CD30 negative malignant T-cells.
Such clear cut cases are a rarity in this business.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com