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Discover LudwigThe phrase "a clear cut difference in" is correct and usable in written English.
It can be used to describe a distinct or obvious distinction between two or more things.
Example: "There is a clear cut difference in the quality of service provided by the two companies."
Alternatives: "a distinct difference in" or "an obvious difference in".
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This could have been due to the general study limitation that there was a clear cut difference between the retrospective and prospective studies in the size of the VOI assessed.
Remember, there's a clear cut difference between being a boss (a horrible one at that) and a leader.
Per cent distributions evidenced a clear-cut difference in walking activities (46.25% in Wistar, 28.4% in DA/Han rats) and in the sniffing activities (45.82% in Wistar, 62.54% in DA/Han).
Our results show a clear-cut difference in the ratio type 1: type 2 transitions in ancient (1∶8) and modern (3∶1) sequences.
Overall, H&E stain showed marked necrosis and neutrophil infiltration within the central focus of infection produced by PVL+ or PVL− strains, but beyond lesion size differences, a clear-cut difference in pathology was not discernable (Figure S3).
This case illustrates a clear-cut difference in performance between GSNCA and GSCA.
In contrast to the EC cell lines, a clear-cut difference in L1CAM promoter methylation of ex vivo tumor tissues was not found.
In these studies, angulation gave a clear-cut difference in local bone turnover between the concave and convex sides of the fracture.
In the 16 specimens showing severe laminar disorganisation and containing an adjacent perilesional area, there was a clear-cut difference in the distribution and signal intensity of gene expression moving from the core of the lesion toward the perilesional area.
An older study that utilized radiological assessment of the bone density in the second metacarpal of normal women and those with pregnancy induced hypertension using the microdensitometry method showed subtle changes in the bone size and densities at various gestations of the pregnancies, but were unable to show a clear-cut difference in the BMD between the tow groups [ 10].
A clear-cut difference in survival with respect of the therapeutic option was found for "early" HCC patients, as well as in our study; for "very early" HCC patients the Authors reported a borderline significance for the decreasing linear trend in survival, with a distinct difference between surgery and TACE, but not between surgery and percutaneous treatments.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com