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VHL mutation or morphological features suggesting a clear cell RCC were not detected.
Both these patients were completely staged and had a clear cell carcinoma (2003 FIGO IIC and 2006 FIGO stage IC); they died from the disease.
Cyclin B1 showed a clear cell cycle phase-specific expression increasing during G2 phase where it was approximately 40% higher when compared to G1 phase.
A clear cell renal cell carcinoma (ccRCC) cell line with homozygous loss of SAV1 has reduced colony-forming capacity when SAV1 is expressed exogenously; additionally, non-tumorigenic renal cells become more proliferative upon SAV1 knockdown [76].
Two are likely papillary RCC, with clear or slightly eosinophilic cells, and two to a clear cell RCC; one shows a mixture of papillary and clear cell RCC architecture.
Contrast-enhanced computed tomography (CT) and magnetic resonance imaging (MRI) are unable to reliably differentiate aggressive RCC variants from benign and indolent tumors [5, 6], particularly when the mass is avidly enhancing, and the clinical question is whether the mass represents a clear cell RCC (ccRCC) or an oncocytoma (the most common malignant and benign renal tumors, respectively).
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The lack of a clear cell-type specification may reflect alterations in normal neuronal and glial proliferation [ 2, 8] and subsequent migration.
A clear cell-to-cell contact between immune effector cells and tumour target cells was noted in biopsies during immunotherapy, Figure 4. We also studied the influence of intratumoural lymphocyte subsets on survival.
From the first time point post-infection at 4 h, DCs and MFs exhibited both core and differential responses to M.tb., showing a clear cell-type dependent transcriptional programme.
Since there is a clear cell-cell interaction in this pathway, what would be the result if one tested the repopulation ability of combined selected cell populations (that is, luminal (Sca1 positive) and basal cells)?
Cortical perforation was common (67%) compared with CEOT without a clear-cell component (6.7%).
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