Sentence examples for a class of transcripts from inspiring English sources
Previously we have shown that loss of UPF2 in hematopoietic cells leads to up-regulated expression of snoRNA host genes, which is a class of transcripts that encodes snoRNA mainly in their intervening introns [13].
Even if it is not a proof of co-localization with ribosome, Hfq co-localization with the ribosomal marker S1 near the inner cytoplasmic membrane as shown here suggests that translation of a class of transcripts that code for membrane proteins may be compartmentalized in this sub-membrane region.
Yet, direct in vivo, genetic evidence of the functional significance of lncRNAs as a class of transcripts remains elusive.
Many of these regions do not have the potential to encode for functional proteins and thus constitute a class of transcripts, popularly annotated as noncoding RNA (5).
GAS5 is transcribed as a 5′-terminal oligopyrimidine (5′TOP) RNA and thus belongs to a class of transcripts characterised by an oligopyrimidine tract sequence at its 5′ end.
Long non-coding RNAs (lncRNAs) are defined as a class of RNA transcripts longer than 200 nucleotides encoded by mammalian genomes that lack protein-coding potential.
Previous studies have described a class of short transcripts (20 90 nucleotides) that originate from the antisense strand in the promoter regions of genes [7] [9], [15].
Activated S6K1 regulates protein synthesis through phosphorylation of the 40S ribosomal subunit, which has been suggested to increase the translational efficiency of a class of mRNA transcripts with a 5′-terminal oligopolypirymidine [40], [41].
7, 8 For instance, RNA-seq has been used to discover enhancer RNA, a class of short transcript directly transcribed from the enhancer region, which contributes to our knowledge of epigenetic gene regulation.
The global term "noncoding RNA" (ncRNA) refers to a large class of transcripts that do not encode a protein product.
Recently, a novel class of transcripts, long non-coding RNAs (lncRNAs), is being identified at a rapid pace.
