Antimicrobial peptides (AMPs) are a class of broad-spectrum antibiotics known by their ability to disrupt bacterial membranes and their low tendency to induce bacterial resistance, arising as excellent candidates to fight bacterial infections.
Carbapenems are a class of broad-spectrum β-lactams identified in the late 1970 s.
A class of broad-spectrum novel ribosome inhibitors (NRI) has been found that shut down bacterial protein synthesis.
Any of a class of broad-spectrum, relatively penicillinase-resistant, ®-lactam antimicrobial drugs originally derived from species of the fungus Acremonium (formerly called Cephalosporium).
Our previous work has demonstrated that N-phenylbenzamide compounds were a class of potential broad-spectrum antiviral agents.
Nucleotide-binding oligomerization domain protein 1 (Nod1) agonists have been shown to boost the inflammatory responses against pathogenic microbes and could thus constitute a new class of broad spectrum antimicrobial agents.
A unique class of broad non-methylated islands encompass polycomb-regulated developmental genes.
That suggested that disease resistance like proteins was a class of genes with broad-spectrum resistance to SCN.
Nitazoxanide 2-acetolyloxy-N- 5-nitroo 2-acetolyloxy-N- 5-nitroNTZ) represents the parent compound of a novel class of broad-spectrum anti-parasitic compounds named thiazolides.
Further modifications of 7d could lead to greater potency and selectivity metrics resulting in a new class of broad-spectrum anthelmintic.
Moreover, IBR2 effectively inhibits the proliferation of CD34+ progenitor cells from CML patients, suggesting that small molecule inhibitors of RAD51 may provide a novel class of broad-spectrum therapeutics for difficult-to-treat cancers (Zhu et al., 2013).
