The phrase "a chronic increase in" is correct and usable in written English.
It can be used to describe a persistent or long-term rise in a particular variable or condition, often in contexts related to health, economics, or environmental issues.
Example: "The study revealed a chronic increase in air pollution levels over the past decade."
Alternatives: "a sustained rise in" or "a continual growth in".
Their data show that a chronic increase in HIF signalling in colon epithelial cells results in increased expression of proinflammatory mediators, the levels of which were decreased by inhibition of the HIF target gene migration inhibitory factor.
"It may well be that continuous exposure to noise for a long time will eventually give rise to a chronic increase in blood pressure," said Dr. Lars Jarup, the senior author and a reader in public health at Imperial College London.
A chronic increase in HIF-2α leads to high turnover of the tight junction protein occludin, leading to a decrease in barrier integrity [17].
To avoid a chronic increase in the unemployment rate, we need to subsidize the demand for labor -- achieving job creation -- rather than making it cheaper to buy capital, as investment and other tax credits would do".
A concurrent report, however, did not observe such a chronic increase in trabecular density.
Any repeated stimulus leading to a chronic increase in stem cell numbers could result in a higher overall frequency of cancer formation [28], [72].
IAP is probably only one of many contributing factors to renal function, and it will be hard to dissect consequences of a slight chronic increase in IAP from other factors related to renal function loss [31].
All operated eyes of animals treated with laser surgery displayed a consistent chronic increase in IOP (Fig 1).
Consistent with its short half-life, these data suggest that the sodium nitrite supplementation produced a small chronic increase in circulating nitrite con-centrations [ 26].
Higher dialysate calcium concentrations have been reported to cause both an acute and chronic increase in arterial stiffness.
However, chronic increase in cortisol levels is harmful to fish31.
