Sentence examples for a chronic elevation of from inspiring English sources
Importantly, the expression of most GR responsive genes identified in this study is also increased in CRH-Tg mice with a chronic elevation of plasma corticosterone levels.
However, a chronic elevation of FFAs as seen in metabolic syndrome is strongly associated with cardiovascular complications [ 1, 2].
Much less is known about the consequences of a chronic elevation of NEFA on the release of somatostatin and glucagon.
The concept that has been put forward is that the proteostasis machinery is overwhelmed when there is a chronic elevation of misfolded proteins.
A transient elevation of IL-6 leads to satellite cell proliferation, whereas a chronic elevation of IL-6 induces the impairment of satellite cell function [ 137].
In addition, a chronic elevation of circulating IL-6 is often associated with an underlying disease, and specific aspects of different disease states could serve to alter the systemic and tissue level response to elevated IL-6.
A possible common denominator in the development of any chronic elevation of blood pressure is the need for the kidney to increase urine volume to promote sodium excretion and, thereby, prevent a chronically expanded extracellular fluid (ECF).
Recent research into hyperfiltration has focused on the relationship between an acute blood glucose rise and eGFR, rather than the effects of a chronic elevation in blood glucose level.
Although some studies indicate an association between chronic elevation of fibrinogen and an increased risk for cardiovascular events [ 37], a systematic review about the safety of fibrinogen substitution in a situation of deficit showed a low thrombogeneity [ 38].
Gout is defined by the presence of monosodium urate crystals which deposit as a consequence of chronic elevation of serum urate above the saturation point for urate crystal formation.
The proposed molecular interaction with BAD is particularly intriguing in the context of mounting evidence that glucose metabolism and therefore GK activation may be critically involved in β-cell hyperplasia as an adaptive response to chronic elevation of blood glucose.
