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Their chief disadvantage is their cost, which is currently so high that a government or private grant is generally required to purchase one.
The chief disadvantage is that the protection against infection afforded by sterile dressings is absent.
Their chief disadvantage is that they fail us over time; used regularly and frequently, they... limit our options and freedom".
Asked how he found flower-show gardening as compared to common gardening, he said that the chief advantages were the absence of pests; the chief disadvantage lack of sunlight.
The chief disadvantage: lower efficiency.
Their chief disadvantage is the lack of necessary authority behind the co-ordination function.
As its chief disadvantage, the cooperative learning environment is difficult to establish and many teachers struggle with the implementation in their classrooms (e.g., Gillies and Boyle 2010).
This is a somewhat arbitrary formula, but it does give you some measure of how much the bargain element in these funds outweighs their chief disadvantage.
According to the American Protein Corporation, which boasts to be the world's largest spray-dryer of blood, the chief disadvantage of blood-based milk replacer is simply its "different color".
Its chief disadvantage is relatively limited tissue penetration.
The chief advantage of this geometry is that the detector accepts more solid angle, and the chief disadvantage is that it must also accept substantial scattered radiation.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com