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However, the ability to predict which chemicals will induce a characterized response in vivo at a particular dose, such as uterine proliferation via estrogen receptor (ER) activation, is much more complex.
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The regulated transport of molecules across the plasma and vacuolar membranes is a well characterized response to abiotic stress [ 26].
A few studies have characterized responses of HeLa cells to Vaccinia infection [30], [31], [32].
Such a framework would combine features characterizing responses to competing demands that show their similarities, differences, and implications.
To date, cellular response assays have been employed mainly in experimental settings to characterize responses to a limited number of known, potent contact sensitizers, but not respiratory sensitizers.
Jasmonate is a well characterized stress response signal that also fulfills hormonal actions in stamen and pollen development [ 55].
A small fraction (11%%) of the total cell population displayed a delayed response, characterized by an initial response weaker than the final response (arbitrarily defined as more than a 50 %-fold difference, Fig. 4b).
In addition, a well characterized dose-response relationship was observed for the decrease in viral load.
To investigate if platelet-cancer cell interactions play a role, we characterized the response of ovarian cancer cell lines to platelets both functionally and at a molecular level.
Exposing yeast to mild stresses, instead, produces a response characterized by a high level of uncoupling [ 53].
Reflecting the importance of ROS as a stress agent, we characterized the response of the biosensor to ROS.
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