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Previously, LMS was not properly distinguishable from gastrointestinal stromal tumor (GIST) until c-kit, a characteristic marker of GIST, was discovered in 1998.
Gastrointestinal leiomyosarcoma (LMS) is a rare entity that could not be accurately diagnosed until c-kit, a characteristic marker of gastrointestinal stromal tumor (GIST), was discovered in 1998 [1].
First, NPY-ir cells are also insulin-ir, the synthesis of the latter hormone being a characteristic marker of beta cells.
Expression of embryonic myosin heavy chain is a hallmark of muscle regeneration after birth and a characteristic marker of human muscular dystrophies.
In addition to morphological transformation, v-Src transformed QNR cells display anchorage-independent growth capacity [8], a characteristic marker of ex-vivo oncogenic transformation.
Additionally, 3% of cells were CD133+, which is a characteristic marker of glial stem cells.
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Analogously to the regulation at the imprinted IGF2/ H19 locus, we tested the hypothesis whether monoallelic binding of CTCF, a characteristic marker for the IGF2/ H19 ICR, also underlies random monoallelic expression.
The increased fatty acid levels in chronically HFD fed rats is a characteristic marker caused due to the dysregulation of insulin and leptin signaling and stimulation of PTP-1B.
Studies on 5-HT reactivity showed hypersensitivity, also expressed as reduced tachyphylaxis (habituation), which successively was evidenced as the most characteristic marker of an altered sensory neurotransmission.
CD44, another characteristic marker of MSC, was also found to be expressed on > 95% of both the MSC and MSC-NTF cells.
Bone disease is the most characteristic marker of end-organ or tissue damage in MM.
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