Sentence examples for a characteristic hallmark from inspiring English sources

We further evaluated the mice for evidence of helper CD4 T cell loss which is a characteristic hallmark of HIV-1 infection.

Lung inflammation is a characteristic hallmark of the allergic response to an allergen.

Hypoxia is a characteristic hallmark of aggressive malignancies, and HIF-1α signalling is upregulated in many tumours.

Early tumor dissemination is a characteristic hallmark of EAC, contributing to the dismal five-year survival of this aggressive disease.

These results permit us to suggest that reduction of WNT7A expression could be a characteristic hallmark in patients with ALL.

The effect that hypoxia exerts on insulin signaling is also of great interest, as insulin resistance is a characteristic hallmark in fatty liver development.

The accumulation of multiple mtDNA deletions is a characteristic pathological hallmark of disorders of mitochondrial maintenance (Copeland & Longley, 2014).

These data suggest that abnormal interactions between a polyQ-expanded protein and its interacting partners may be responsible for toxicity and cell loss in polyQ diseases 7. A characteristic pathological hallmark in polyQ diseases is the formation of large inclusion bodies with insoluble protein aggregates in the nuclei of affected neurons.

Overall, close similarities in BPA-activated proliferation endpoints in HRBECs and in T47D breast cancer cells support a role for BPA in the promotion of characteristic hallmark cancerous traits of continuous proliferation and apoptosis evasion in high-risk cells that have not yet become malignant.

Our results clearly demonstrate that single injection of oxaliplatin induces a dose-dependent development of neuropathic signs with the characteristic hallmark of enhanced cold perception.

In lesions with astrocyte loss, the characteristic hallmark for tissue injury was loss of AQP4 and a pattern of astrocyte dystrophy, which bears similarities to astrocyte clasmatodendrosis.