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The phrase "a characteristic difference in" is correct and usable in written English.
It can be used when discussing distinctions or variations between two or more subjects, particularly in a descriptive or analytical context.
Example: "There is a characteristic difference in the way these two species adapt to their environments."
Alternatives: "a notable distinction in" or "a defining difference in".
Exact(1)
For example, Craniata QSOX1 and QSOX2 show a characteristic difference in the number of amino acids linking the Erv domain to the membrane.
Similar(59)
In addition, EELS investigations of the amorphous material in the hollows and at the shoulders of the ripples could verify the presence of a-Si due to characteristic differences in the respective silicon L2,3 edges.
These observations suggest that the overall representation of individual VH genes in peripheral B cells in the present RA patient resembled the repertoire expected in an adult, but also contained characteristic differences in certain genes already seen to often be biased in autoimmune diseases.
Cultural differences in socialization can lead to characteristic differences in how we perceive the world.
We identified the characteristic differences in gene expression between HepG2 cells and liver tissue.
Namely, the characteristic differences in VSMCs likely depend on cell origin during prenatal development.
This indicates characteristic differences in the replication features and in the pathobiology of these two virulence variants.
In vitro measurements point out characteristic differences in calcium sensitivity of activation between CaMKII isoforms [ 19, 20].
Interestingly, such features of the assembled sequence actually point to characteristic differences in genomic architecture among species.
This study found striking gender-based anthropometric and BIA characteristic differences in black South African HIV-positive individuals on HAART.
Of further note, melanoma and melanocyte cell lines did not display characteristic differences in changing transcription profiles.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com