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In such a situation the question remains that a changed paradigm in chemotherapy should be adopted targeting the co-infections.
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Circumstances do not change, paradigms shift.
A single-blind, sham-controlled, between-group design was used to assess the effect of on-line (i.e., stimulation overlapping with the critical task) tVNS in healthy young volunteers (n=30)–on a stop-change paradigm.
More recently, Tseng and Bridgeman (2011) reported superior performance in a change detection paradigm when the changed object was near the hands.
Gehl says he detects "a change of paradigm" with planners to human-scale cities, citing his home city of Copenhagen as a model.
"We need a change in paradigm, and we need like the good Samaritan to consider the situation from the position of someone who suffers and asks for help," he said.
In contrast, today, there is a change in paradigm.
"There has been a change of paradigm in the way companies and entrepreneurs are financing themselves.
Along those lines, a scientific revolution is characterized by a change in paradigm.
This paper calls for a change in paradigm in lot sizing and scheduling.
Finally, the triple-learning loop corresponds to a change of paradigm, a transformation of the planning processes.
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CEO of Professional Science Editing for Scientists @ prosciediting.com