Both types of stimulation yielded a similar fraction of significantly changed functional connections and the magnitude of changes agreed very well (Table 1).
Deamidation of Bcl-xL, with consequent abolishment of its antiapoptotic function, thus represents a further example of such a molecular device to change functional properties of those proteins in which it occurs.
It was shown that the interhemispheric functional connectivity for both motor cortex as somatosensory cortex was changed following limb deafferentation [24] and after stroke a changed interhemispheric functional connectivity for the somatosensory cortex was shown [13].
The U.S. EPA defines an adverse effect as "a biochemical change, functional impairment, or pathologic lesion that affects the performance of the whole organism, or reduces an organism's ability to respond to an additional environmental challenge" (U.S. EPA 2013).
Adversity encompasses a range of functional impairment; the U.S. EPA Integrated Risk Information System (U.S. EPA 2005b) defines an adverse effect as "a biochemical change, functional impairment, or pathologic lesion that affects the performance of the whole organism, or reduces an organism's ability to respond to an additional environmental challenge".
(8) Maintenance, rehabilitation, and reconstruction of facilities that occupy substantially the same geographic footprint and do not result in a change in functional use, such as: Improvements to bridges, tunnels, storage yards, buildings, stations, and terminals; construction of platform extensions, passing track, and retaining walls; and improvements to tracks and railbeds.
The precise conformation (or dynamics) of the new loop is not trivial to predict preventing reliable interpretation of a change in functional state.
The analysis revealed a change in functional connectivity (FC) in one pair of brain regions, left fusiform gyrus (LFUS) and left parietal lobe (LPAR) with L-dopa.
Finally, the present study relies on the assumption that there is a change in functional connectivity induced by the change in condition from rest to task, and that this change was fully captured by the correlation matrix.
The second primary outcome measure was a change in functional limitations of activities of daily living.
