The phrase "a change in functionality" is correct and usable in written English.
It can be used when discussing modifications or updates to the features or capabilities of a system, product, or service.
Example: "The latest software update includes a change in functionality that allows users to customize their dashboard."
Alternatives: "an alteration in functionality" or "a modification of features".
Mutations in these spots may lead to a structural change that directly relates to a change in functionality.
Wobble, which lets you add "jiggle points" to any photo (use your imagination) hasn't released a change in functionality for 6-8 months, and has been installed 970,000 times — none of these were flying under Apple's radar.
Finally, subfunctionalization occurring by tissue- or developmental stage-specialization of gene expression without a change in functionality would result in retention of stabilizing selection action in both paralogs.
By "flipping" the high input signal from 5 to 1.5nM, we obtain a change in functionality, from NOR to NAND (negated AND).
Women may objectively have poorer functionality but do not regard this as a problem, or women may be more active in the home than their retired partners and therefore more aware of a change in functionality, or women may be more aware of their own health and therefore report health problems in a higher proportion than men.
Furthermore, Fas undergoes a change in its functionality in oxaliplatin-resistant cells inducing survival pathways instead of apoptotic signals.
As it is shown in Figure 7C, activation of Fas by CH11 lead to a higher upregulation of these proteins in the resistant cell line compared to the non-resistant cells, pointing to a change in the functionality of the receptor in cells that have acquired resistance to apoptosis-induction by oxaliplatin.
In this work, we have demonstrated, to our knowledge, for the first time that when colon cancer cells acquire resistance to oxaliplatin a change in Fas functionality develops, and a receptor switch occurs: from activation of apoptosis to stimulation of MAPK pathways.
The variants chrX:15863648GA > G and chrX:135115669GA > G, for example, occur in homopolymer intronic regions outside the invariant splice site, and thus are unlikely to result in a change in protein functionality and would not be considered for in-depth review.
It is commonly assumed that when something happens at a higher level (e.g. a change in some tissue functionality, say the beating of the heart), something also happens at the molecular level.
It has not been investigated if a change in histone modifications hampers functionality of the sperm.
