The phrase "a challenging question for" is correct and usable in written English.
It can be used when introducing a question that poses difficulty or complexity for a specific person or group.
Example: "This is a challenging question for anyone trying to understand the nuances of climate change."
Alternatives: "a difficult question for" or "a tough question for".
A challenging question for tissue engineering and regenerative medicine is whether the presence of molecularly different osteogenic proteins of the TGF-β superfamily has a therapeutic significance.
With such a shift the ability of existing ventilation systems in meeting the new requirements is a challenging question for researchers.
The behaviour of these women raises a challenging question for the rest of us: when killers strike in this way, should we listen to what they have to say?
"Whether conditional response is a basic decision-making mechanism of the human brain or just a consequence of more fundamental neural mechanisms is a challenging question for future studies," they say.
Optimal subject number is a challenging question for preclinical studies.
To determine the mode of sex determination is a challenging question for many species [ 18].
The suitability of NO diffusing capacity is in line with previous observations in healthy subjects or patients with other diseases than CF [ 25] and renders it a challenging question of whether the combined diffusing capacity for NO and CO has a potential to be included in the assessment of CF. In this respect, the conclusions of this retrospective cross-sectional study can only be limited.
While numerous gene mutations can be identified from each cancer genome, what these mutations mean for cancer is a challenging question to address, especially for those from less understood putative new cancer genes.
I think a more challenging question for those who advocate more decentralisation is how you deliver a strategic solution that coordinates overlapping departmental public services, if decisions are being made by local agencies or managers.
They might have framed a more challenging question for the president.
The mechanisms behind the great diversity of arthropod Dscam1 forms containing new variable domains consistently emerging is not just a challenging question in neurobiology, but is equally important for our understanding of evolutionary processes in general.
