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It is now celebrating its 60th year, while in a temporary home at the Lowry in Salford, producing a challenging mixture of contemporary drama and modern classics.
In 1998, Bolaño published his best-known work, the sprawling novel Los Detectives Salvajes (The Wild Detectives), a challenging mixture of thriller, philosophical and literary reflections, pastiche and autobiography, which he baptised "infrarealism".
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The method was applied to nucleotides and activated sugars of animal cells and of green plants, which harbor an especially challenging mixture of nucleotide sugars, e.g., the only recently noticed multitude of UDP-pentoses.
Often linking aggressive hardcore beats, trance patterns, Caribbean rhythms, and pop hits in a challenging, ever-changing mixture, Toxe proved herself a master at this brave new sound.
However, reliable estimation of the T-F mask from sound mixtures is a challenging task, especially when room reverberations are present in the mixtures.
Model-based design of separation processes for heterogeneous azeotropic mixtures is a challenging task.
The separation of azeotropic mixtures is a challenging task that is currently performed by special distillation processes, such as heteroazeotropic, extractive or pressure-swing distillation.
However, because of limited understanding of their degradation behavior even for single component plastic wastes, modeling degradation kinetics of plastic mixtures is a challenging task.
The separation of pure CNT, especially SWCNT, from their mixtures is a challenging jobs, since they posses many common features with the MWCNTs, making the traditional separation techniques inefficient.
Despite the fact that a stand-alone ideal heat-integrated distillation column (ideal HIDiC) can be thermodynamically efficient and operationally stable, the application of an ideal HIDiC system to separate a close-boiling multi-component mixture is still a challenging problem because of the possibility of strong interactions within/between the ideal HIDiCs involved.
Chemical composition analysis of these mixtures is therefore a challenging task.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com