Recognition of the RTM's ability to support the regeneration of cellular and vascularized soft tissue and the transition to a tissue architecture resembling that specific to the treated site has fueled use by clinicians for new and challenging indications.
9– 11 Treatment of the tear trough is one of the most challenging indications in facial rejuvenation.
Therefore, decision making about the proper indications and timing of ECMO is a challenging problem for physicians who manage patients with severe acute respiratory failure.
Although these behaviours are indication of driver aggressiveness, detection of these behaviours in real time is a challenging task.
Providers may also misinterpret the signs of a challenging re-adjustment as opposition to treatment, lack of motivation to change or reintegrate, proof of individual pathology, or indications of a serious mental illness (Rotter et al. 2005).
after a challenging summer.
And a challenging business.
It is a challenging task.
It was a challenging situation.
