Sentence examples for a challenging and large from inspiring English sources

Solving large-scale scientific problems represents a challenging and large area in numerical optimisation.

As a consequence, realistic simulations with N ∼ 10 6 - 7 for globular clusters and galactic centres are still very challenging and large parameter studies impossible.

However, de novo assembly is still challenging and large amounts of true SVs may be lost during the assembly process.

And I would say that Frank has done a pretty significant task of legislating with such a challenging and diverse committee that's so large," says Rep. Patrick McHenry (R-N.C ., a committee membeR-N.C .

The control of their size and shape is a challenging goal, and a large number of reports have been published for the preparation of metal nanoparticles of various morphologies [1 5], mainly for plasmonic and sensing applications [6].

A control of these parameters is a challenging goal, and a large number of reports have been published[13 20].

Transport studies in the ex vivo intact placenta are technically challenging and require large quantities of substances to be tested.

These tests are time-consuming, technically challenging, and require large volumes of freshly drawn citrated blood, which is an important drawback in studying young children.

With this Cayley-transformed DNS-based Krylov method two flow cases were successfully investigated: (i) a compressible mixing layer, a rather simple but well-known problem, which served as a test case and (ii) a supersonic flow about a swept parabolic body, a challenging large-scale flow configuration.

Datacentric applications are still a challenging issue for large-scale distributed computing systems.

Moreover, accessing the data needed for a specific downstream application scenario is a challenging task in large-scale BIM projects.