Although measurement of total fat and three-dimensional (3D) reconstruction and quantification of various fat depots can be done routinely and reliably with MRI aided with 1D MRS (magnetic resonance spectroscopy) (Liu et al, 2010; Springer et al, 2010), it remains a challenge to determine the extent of saturated and unsaturated lipids within a tissue compartment.
Another key finding from this study is that the propensity of mice to reinstate was not correlated with the propensity to sensitize to a challenge dose of cocaine or the extent of CPP originally observed.
The complex anatomy of the joint together with the frequent finding of complex patterns of structural lesions that occur in combination on the same MRI slices may also challenge reliable estimation of extent of involvement that is based on number of erosions per joint or percent of subcortical bone affected.
A central challenge is the extent of Kurdish power and independence.
Austria's Supreme Court is referring a legal challenge over the extent of Facebook's responsibility to remove hate speech postings to Europe's top court for an opinion (via derStandard.at).at
Configuring a sixth stage in the historical evolution of health as a human right and socially determined poses the challenge of identifying the extent to which health assets model is known and capable of being implemented.
Moreover, studies on within-host virus evolution pose the analytic challenge of assessing the extent to which artifacts mask genuine patterns of nucleotide substitution.
That may change, if ever connections grasp the nettle and set him a challenge that might explore the extent of his latent resources – perhaps by dropping him to two and a half miles at Aintree, where he would meet Champion Hurdle types halfway.
I saw for myself in Lebanon the scale of the refugee challenge, the extent of the education aspiration, and the immensity of the danger should we fail.
Finally, scientists are faced with the daunting challenge of definitively deriving the extent to which a landform or landscape has or will continue to change in response natural and/or anthropogenic processes.
In part because of the challenge of ascertaining the true extent of transmission, health departments elsewhere have believed the SARS epidemics to be under control, only to find later that spread had occurred beyond what was recognized.
