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In the evolutionarily highly conserved ubiquitin-proteasome pathway (UPP), a protein is "tagged" for degradation by the proteasome, when it is labeled with a chain of multiple ubiquitin molecules [ 1].
Thus, evidence of superiority from the stage IV setting should be the 'tipping point' for launching a chain of multiple rapid trials in early disease, in the same way that any societal emergency should be handled when thousands of lives are at stake.
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In contrast, a loop design compares two conditions via a chain of other conditions or multiple-pairwise (interwoven loop) fashion [ 9, 10].
The identity of the source of a material may be lost in the chain of multiple exchanges and amalgamation with others unless the link to a "mother resource" is traceable.
Mr. Broda began his career as a fashion designer, ultimately operating a chain of 120 stores, under the "Multiples" brand, across France.
I'm beginning to think there's actually no deeper meaning to this third installment of The Human Centipede, and it is just a film about a chain of excrement winding its way through multiple peoples conjoined digestive tracts.
I'm beginning to think there's actually no deeper meaning to this third installment of The Human Centipede, and it is just a film about a chain of excrement winding it's way through multiple peoples conjoined digestive tracts.
I'm beginning to think there's actually no deeper meaning to this third instalment of The Human Centipede, and it is just a film about a chain of excrement winding it's way through multiple peoples conjoined digestive tracts.
Often, ubiquitin is not only conjugated as a single moiety, but rather forms chains of multiple ubiquitin molecules linked via isopeptide bonds between the C-terminal glycine residue of ubiquitin and one of the seven internal lysine residues of the preceding ubiquitin in the chain.
Dangerous areas are navigated through a sort of chessboard interface in which you position your character to enter chains of multiple fights to earn the most currency for purchasing weapons and equipment.
Mirzapour Al-e-hashem et al. (2011) proposed a multi-site, multi-period, multi-product aggregate production planning problem in a supply chain consisting of multiple suppliers, multiple plants and multiple customers under cost and demand uncertainty.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com