To compare the minimum number of reads needed to reach a certain coverage under the assumption of equal amplification efficiencies between alleles (T1Galan Simul) and taking variation in amplification efficiency into account (T1Simul VarAmplEff), we used a simulation approach based on random drawings in a multinomial distribution.
For example, the requirement of providing a certain coverage while certain nodes can sleep is a well known problem in sensor networks [7, 8].
Some travel insurance providers require proof of current medical conditions and exclude certain coverage because of those conditions.
Increasing sequence coverage of MP data has impact on assembly statistics, but upon reaching certain coverage, added value of additional MP sequencing may not justify the cost of data generation.
Based on a binomial distribution, the expected coverage of a target sequence given a certain depth of coverage or level of redundancy, R, can be approximated by the equation: E(Coverage) = 1 - e-R Based on this relationship, for a 15 kb mt genome and a mean sequence read length of 200 bp, approximately 500 reads of mitochondrial sequence are needed to obtain full coverage.
A very unusual feature of the assembly was that under certain coverage cutoff regimes, a fragment of the mitochondrial sequence was omitted.
Since our study was performed for finite, using our results on various features of path coverage, one can find the necessary number of sensors for a certain quality of coverage.
For instance, we might choose to consume enough data to maintain a certain level of coverage, but not consume excessive data if doing so results in little change in coverage.
The cause of the injuries was "the failure of the plan itself to cover the requested treatment," Justice Thomas said, reflecting the managed-care industry's argument that it should not be blamed when an employer has, for economic reasons, declined to buy a certain level of coverage.
In [15], Ye et al. first calculate the ideal density for providing a certain fraction of coverage.
