The phrase "a certain conformation of" is correct and usable in written English.
It can be used when referring to a specific arrangement or structure of something, often in scientific or technical contexts.
Example: "The study focused on a certain conformation of the protein that is crucial for its function."
Alternatives: "a specific arrangement of" or "a particular structure of".
For a certain conformation of the macromolecule, its 3D density V thus can be written as V = V_{1} cdot E_{1} + V_{2} cdot E_{2}, (1 where E 1 and E 2 are the Euler matrix of V 1 and V 2, respectively.
R683G may increase the flexibility of the linker region between the two lobes of the pseudokinase domain [30] and in doing so could require a certain conformation of the JH2 αC, which is lost when F595A is present.
Kinase inhibitors often recognize a certain conformation of a kinase and stabilize this state during crystallization.
It has been suggested that the extra domains contribute to the catalysis by stabilizing a certain conformation of Switch II (Kupzig et al., 2006; Kupzig et al., 2009).
Grøndalen [ 26] proposed that a certain conformation of the stifle joint causes local overloading in an area of the femoral condyle, which results in OC.
As the probability of each conformation differs according to its stability (Equation 1), the exposure probability of a certain conformation is multiplied by the probability of the corresponding conformation to obtain the overall RDS-exposure probability.
These APP-targeting manipulations may alter APP conformation, its positioning within the membrane, APP substrate presentation to γ-secretase, and/or stabilize PS1 in a certain conformation, and thus affect the site of APP cleavage by γ-secretase.
The authors are left with the speculation that the polymer may lock the subunits into a certain conformation, and block its switch to another conformation needed for activity.
Further, as integrin binding of Opc relies on prior binding to RGD-containing ligands, this interaction may not be observed as these ligands were not supplied and because integrin binding to its ligands requires certain conformation of the heterodimeric receptors (Boettiger et al., 2001).
Hence, it is possible that mAbs recognize certain conformations of epitopes which are not displayed in the same structural context by the natural antigen.
