The phrase "a certain and substantial" is correct and usable in written English.
It can be used when describing something that is both definite and significant in amount or degree.
Example: "The project requires a certain and substantial investment of time and resources to be successful."
Alternatives: "a definite and considerable" or "a specific and significant".
The effects on hESC researchers "would be certain and substantial.... Their investments in project planning would be a loss, their expenditures for equipment a waste, and their staffs out of a job," the decision says.
It doesn't make much sense, though, to impose certain and substantial costs on the economy now in order to avoid unknown and perhaps even benign changes in the future.
These are real phenomena which deserve further study". Ultimately, at Wikipedia there is a certain substantial body of editors who embody "pathological skepticism" and who do not allow good evidence from high-quality studies and meta-analyses published in high-impact journals to be included into the body of evidence for homeopathy just because they provide a positive spin to the subject.
Precisely, executing a processing step each time a small fragment of data arrives can have a great impact on performance, as opposed to executing only when a certain substantial quantity of new data is available.
This means that unless a development activity occurs too close to one of Singapore's National Parks, or unless a certain activity generates substantial public outcry, EIAs are not implemented, unless they are carried out by developers in 'good faith'.
The present study based on hypothetical scenarios indicates that if the price of preventive medication increases above a certain threshold, a substantial proportion of the population may refrain from treatment.
The soup should be tending towards a certain thickness and body – not gloopy, but substantial.
He learned that because the gallery had not exercised a certain tax option, a substantial obligation would be incurred if it sold off its inventory.
When business partners have a falling out, or firms are battling over the ownership of intellectual property or the value of a certain deal, peacebuilders with substantial background in the business world can be of help.
