The phrase "a central question about" is correct and usable in written English.
It can be used when discussing a key issue or topic that is being examined or analyzed in a particular context.
Example: "In the study of climate change, a central question about the impact of human activity remains unanswered."
Alternatives: "a key issue regarding" or "a fundamental question concerning".
It's a central question about performance.
It seems like a central question about the experience of being alive.
Thus a central question about Mr. Bush is simply how transferable his style would be to Washington.
The discussion circled back repeatedly to a central question about Kline's project: "What is the medium?" This is both a deep philosophical query and, for an archivist registering works or a lawyer defining them in contracts, an urgently practical one.
The intensified assault by religious leaders poses a central question about Mr. Giuliani's viability as a Republican presidential candidate and presents him with one of his first big tests on the stump.
In their quest, prosecutors have raised a central question about the role of the students — suggesting that they should be viewed as an "investigative agency," not journalists, whose unpublished materials could, under certain circumstances, be protected under a state statute.
At the heart of all this is a central question: What about Russia and the U.S.? Are we historic rivals?
It might be a quartet of north European conservatives, but in Brussels the Swedish sojourn has already been dubbed an Anglo-German summit focused on a central question – what to do about Jean-Claude Juncker.
Like many of those interviewed, Father Bullock said he was most disappointed that the cardinals ignored a central question: what to do about the senior church leaders who transferred the priests accused of sexual abuse from parish to parish.
A central question is whether information about effectiveness of interventions is transferrable between countries.
A central question in the debate about exploitation in international research is whether investigators and sponsors from high-income countries (HIC) have obligations to address background conditions of injustice in the communities in which they conduct their research, beyond the healthcare and other research-related needs of participants, to aspects of their basic life circumstances.
