An elderly person can gain access to funding from this act by applying for an indication at what is called, the Central Indication Organ (Dutch: CIZ).
For example, Besnard et al. [7] applied a transformation rule approach to the design of novel dopamine receptor type 2 (Dreceptoreptor active compounds with specific polypharmacological profiles and appropriate DMPK profiles for a central nervous system indication.
Electric currents can be used to replace the weight or spring as a source of power and as a means of signaling time indications from a central master clock to a wide range of distant indicating dials.
The inclusion criterion was either the presence of or a clinical indication for a central venous catheter.
Indication for a central venous, PAC or CCO catheter was left to the discretion of the attending physician.
Between January 2006 and March 2007 a total of 340 patients, all 18 years or older, with a clinical indication for a central venous catheter (CVC) (BD Medical Systems, Singapore), pulmonary artery catheter (PAC) (Edwards Lifesciences LLC, Irvine, CA, USA) or Continuous Cardiac Output (CCO) catheter that measures SvO2 continuously (Arrow Deutschland GmbH, Erding, Germany) were recruited.
Ninety-eight consecutive unplanned admissions to a multidisciplinary ICU (median age 63 [range 19 to 83] years, median Simplified Acute Physiology Score [SAPS II] 43 [range 11 to 92]) with a clinical indication for a central venous catheter were included in the study.
The clinical indication for a central venous catheter was determined by the attending physician, and patients were enrolled in the study only if the first blood sample from the central venous catheter was obtained within the first two hours after ICU admission.
All patients had a medical indication for both a central and a peripheral venous catheter and were admitted to the intensive care.
Further investigation on this topic is needed, as it is a central construct in recent debates on indications for applying shared decision-making.
