Sentence examples for a central effect of from inspiring English sources

BEHIND THE NEWS The deep slump in the housing market is both a central cause and a central effect of the credit crisis and the economic slowdown it is driving.

Yet, we do not have sufficient data to confirm or refute a central effect of PACAP38-induced migraine-like attacks.

More evidence for a central effect of ASA on pain processing is coming from an imaging study investigating pain ratings as well as stimulus evoked responses to nociceptive stimulation using an electroencephalogram (EEG).

Epigenetic de-regulation has been suggested to be a central effect of the aberrant expression of SYT-SSX and a possible mechanism underlying synovial sarcoma formation.

Physical exercise has been shown to reduce MSNA in heart failure [18] and to alter HRV in type 2 dianeffect1], an effect proposed to originate from a central effect of training [22].

However, a central effect of significant prevalence of the amygdala and hippocampus activation with eyes closed over eyes open state remained for both negative (amygdala: (t(5) = 1.8, p<0.05; hippocampus: t(5) = 2.2, p<0.05) and neutral stimuli (amygdala: t(5) = 3.8, p<0.05; hippocampus: t(5) = 2.3, p<0.05).

It is quite clear that the hyperthermic effects of TRPV1 antagonists are not a central effect through regulation of hypothalamic TRPV1 channels involved in body temperature control, and nor are they a thermosensor response through inhibition of heat-activated TRPV1 [ 29].

The ability of an NSAID to have a central effect through penetration of the blood brain barrier is variable and depends on various molecular characteristics such as size, lipid solubility, and capacity to bind to plasma proteins [ 15].

Therefore, although crossing of the BBB is likely to occur to some extent – telcagepant has been detected in primates cerebrospinal fluid, suggesting its presence in the CNS [53] – a central effect – and side effect – of these drugs seems unlikely.

They found a central effect unlikely because no central effect of sumatriptan was observed in previous studies [9, 10] cZolmitriptan 30 μg/kg caused a decrease in c-fos expression in trigeminal nucleus caudalis dThe site of action is not totally clear but is most likely a CNS effect because a reduction of contralateral allodynia [29].

It has been discussed whether a defect in the BBB during migraine attacks could be responsible for a possible central effect of sumatriptan in migraine.