The phrase "a central difference between" is correct and usable in written English.
You can use it when discussing or comparing two or more items, concepts, or ideas to highlight a significant distinction among them.
Example: "A central difference between the two theories is their approach to understanding human behavior."
Alternatives: "a key distinction between" or "a major contrast between".
A central difference between the proposals is how much they devote to state and local preparedness.
"A central difference between those cases Colonnade and Biswell and this one is that businessmen engaged in such federally licensed and regulated enterprises accept the burdens as well as the benefits of their trade, whereas the petitioner here was not engaged in any regulated or licensed business.
He suggests that a central difference between human and merely animal activity is our capacity to reflect on our desires and beliefs and form desires and judgments concerning them.
A central difference between the two drugs is that only the ribo analog exerts downregulation of RNA on day 2. All RNA species are downregulated, but this appears to be distinctive for small RNA species such as miRNAs and tRNAs.
A central difference between the two is that the Stratonovich SDE uses the usual deterministic calculus whereas the Ito SDE requires a completely new stochastic calculus.
When Lillywhite says he can see greatness in more artists than Simon, he means the central difference between them is their idea of what can make a star.
The most central difference between effect modification and confounding is that "whereas confounding is a bias that the investigator hopes to prevent or remove from the effect estimate", effect modification is a real effect and "a property of the effect under study" which the investigator wants to report in the findings [ 37], p.254.
The central difference between the administration's proposal and Dr. Koplan's is the amount each would spend on state and local public health preparedness.
The big difference between TmPPase and VrPPase is in the position of K16.50; indeed this is the most significant difference in the entire active site and so must be related to the central difference between the proteins their pumping specificity.
Mr. Liebman said the central difference between his candidate and Mitt Romney was the president's view that trickle-down economics doesn't work.
The central difference between the two concepts is the fact that the right of privacy was transferable, which benefitted corporations and third parties, whereas the right of publicity originally was not.
