Sentence examples for a cellular transformation from inspiring English sources

On the other hand, our work has shown that over-expression of DDX3 brought about a cellular transformation leading to the down-regulation of E-cadherin expression in immortalized breast epithelial cells (MCF 10A cells) [19].

In NETosis, certain activating influences can trigger a cellular transformation in which the nuclear membrane breaks down, DNA mixes with cytoplasm and the whole assemblage is jettisoned from the cell, providing a key ingredient for pus and other exudates.

Although its role as a tumor suppressor is not established, its absence might serve as a biomarker for cellular transformation in a tissue/cell-specific manner.

Another tumor suppressor gene product, PDCD4 (programmed cell death), was originally characterized as an inhibitor of cellular transformation in a mouse cell culture model [ 29].

The virus exists as an episomal chromosome for an indeterminate amount of time within a cell until cellular transformation occurs and the virus integrates into the host genome [ 15].

Although all of the viral proteins have a role in viral replication, only a small number of the viral early proteins have a role in cellular transformation.

Anchorage-independent growth is a hallmark of cellular transformation.

Finally, we suggest that the downregulation of WFDC1 might serve as a biomarker for cellular transformation.

Moreover, experimental evidences indicate that Rho GTPases play a role in cellular transformation.

Taken together with the results from other groups, our data implied CIP2A might be a prerequisite to cellular transformation.

However, our results indicate that other oncogenic miRNAs within this megacluster also play a role in cellular transformation (Fig. 2H).