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Our replication strategy used tag-SNPs selected based on linkage disequilibrium, because variation in linkage disequibrium between SNPs in different populations is a cause of failed replication in GWASs [11], [28].
In particular, the use of a strong tertiary amidine, DBU, as Nα-deprotection base was required for the successful assembly of the B chain; this highlights the need to consider incomplete deprotection rather than acylation as a cause of failed synthesis.
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Progressive hypoxemia after extubation is a common cause of failed extubation [ 8] and might be predicted by a high fraction of inspired oxygen (FiO2) and/or positive end-expiratory pressure (PEEP) requirement, or a reduced arterial oxygen partial pressure (PaO2):FiO2 ratio [ 7].
Epidural fibrosis resulted from epidural fat destruction following laminectomy operation is regarded as a main cause of failed back surgery syndrome, which represents one of the most common complications in spine surgery.
We have noted that inadequate drug delivery to tumor cells is a major cause of failed intravesical therapy for nonmuscle invading bladder cancer, partly due to the dilution of drug concentration by urine production during treatment.
Trunnionosis is a well-known cause of failed total hip arthroplasties.
"Poly A tail" was the single largest cause of failed sequence in both the template-related failure category as well as the entire data set, yet the reads make up the majority in the higher failed read length bins.
"While the number of incidents remains small, and Tesla's review to date points to the building receptacle or wiring as the primary cause of failed NEMA 14-50 adapthes, the Company has determined that a voluntary recall is appropriate as a precautionary measure".
Difficult anatomy has been reported as the primary cause of failed intubation by prehospital providers in 20% of the cases, along with clenching (49%) and airway obstruction (10%) [6].
Although the cause of lethality of TANK1−/−TANK2−/− or TANK1+/−TANK2−/− embryos is not fully defined, the lack of umbilical cord and failure of placental development may constitute the cause of failed embryonic development.
The main cause of failed cloning and expression of 250 out of 600 VCs from Neisseria meningitidis B was the presence of more than one transmembrane spanning region (TM) [ 12].
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CEO of Professional Science Editing for Scientists @ prosciediting.com