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Furthermore, oxLDL is toxic at higher concentrations and thus could be a cause of cell death in lesions [156].
Apoptosis was observed in the injured brain cortex and white matter in a study using mild TBI models, indicating that TBI was a cause of cell death [30].
The generation of reactive oxygen species beyond the capacity of a balanced redox regulation in cells is probably a cause of cell damage.
So it is important to clarify whether the decreased expression of cyclin A2 is a cause of cell differentiation or a result of differentiation response.
Several lines of evidence suggest that the ERC accumulation may be a cause of cell aging in S. cerevisiae, and introduction of artificial ERCs shortens lifespan of yeast cells (Sinclair & Guarente, 1997).
In neuroblastoma, the expression of nuclear CLU is marginal and we have only observed this variant in terminally necrotic or apoptotic cells, suggesting that its expression is a consequence rather a cause of cell death in physiological conditions.
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The findings raise the possibility that high blood pressure may be a cause of renal cell cancer.
The weight of the evidence to date, however, does not provide consistent, credible support for the hypothesis that TCE is a cause of renal cell cancer in humans.
An increase in mitochondrial oxidant production is generally accepted as a cause of myocardial cell loss via apoptosis and necrosis [ 50].
The earlier finding that ectopic expression of BCL11B in HeLa cells caused cell cycle retardation inspired the authors to develop a hypothesis of unscheduled proliferation as a primary cause of cell death in Bcl11b-depleted cells.
Oxidative stress has been considered as a major cause of cell damage in various neurodegenerative disorders.
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CEO of Professional Science Editing for Scientists @ prosciediting.com