The phrase "a cause for substantial" is correct and usable in written English.
It can be used when discussing reasons or factors that lead to significant outcomes or effects.
Example: "The recent changes in policy have become a cause for substantial concern among the community."
Alternatives: "a reason for considerable" or "a source of significant".
The persistence of DDT and its more stable metabolite DDE (dichlorodiphenyldichloroethylene) in sediments and the food web and its intense bio accumulation in apex predators is the cause for substantial monitoring and continued concern over potential health effects.
In PCA, the first principal component (i.e., development stage) was estimated to explain ~83% of variance in the seed transcriptome, indicating that embryogenesis is the predominant cause for the substantial variation observed in the transcript population.
The cause for this substantial expression in the placentae of pregnancies complicated by either gestational diabetes or PE could be the developing or existing fetal stress (Kralova et al., 2008).
A substantial cause for optimism is the high degree of engagement shown by people with ARF/RHD, with up to 90% attending the clinic within a three-month period, usually for ARF/RHD care.
Community-acquired pneumonia (CAP) is a major cause for hospitalization and has a substantial impact on health care costs [ 1].
Voting for military action in Iraq provided a cause and focus for a substantial increase in worldwide terrorism and has since led to almost 500,000 civilian deaths in Iraq; the vote in 2013 for no military action in Syria increased the civilian deaths there and gave Assad the confidence to continue using chemical weapons.
Furthermore, by undertaking standardised verbal autopsy (VA) enquiries to follow-up deaths, cause-specific mortality can be assessed within specific childhood age groups to see which cause groups account for substantial components of overall mortality (6).
Peripheral nerve injuries represent a major cause for morbidity and disability and pose substantial costs for society from a global perspective.
Q: What are the key causes for the substantial income gaps in the United States today?
Factors within the built environment (for example, demographics, location, living condition, building conditions, and means of communication) constitute the major causes for the substantial exposure of human settlements to disasters or public health emergencies (Cruz 2007; Schwab et al. 2007).
