The phrase "a causative role in the development" is correct and usable in written English.
It can be used when discussing the influence or contribution of a factor in a process or outcome, particularly in academic or scientific contexts.
Example: "The study aims to explore the causative role in the development of certain diseases."
Alternatives: "an influential role in the development" or "a contributing factor in the development."
These observations might be interpreted either as an indication that GH does not play a causative role in the development of diabetes or, alternatively, that diabetes develops above a GH threshold dose and IGF-I concentrations and that patients at risk for developing diabetes do so early after initiation of GHRT.
CLIP has already been recognized as a factor that plays a causative role in the development of sarcopenia.
Amyloid beta 42 peptide (Aβ1 42) is believed to play a causative role in the development of AD.
Acting under the assumption that overexpression of FRG1, FRG2 or ANT1 plays a causative role in the development of FSHD, transgenic mice were generated expressing each of these individual genes under the human skeletal actin promoter, specific for expression in muscle, which resulted in the identification of a potential mouse model for FSHD.
Ultraviolet radiation is believed to play a causative role in the development of cataract.
Oxidative stress is thought to play a causative role in the development of AD [ 152, 153].
So far MCC is the only tumour type where MCPyV has been shown to be present and integrated in the cellular genome, suggesting a causative role in the cancer development.
Thus, Aβ42 is thought to play a causative role in the pathogenesis of AD [4].
Estrogen deficiency plays a causative role in the activity of osteoclasts.
Although some studies found that patients with mitochondrial diabetes are insulin resistant (8), others reported normal insulin sensitivity, suggesting that the A3243G mutation in skeletal muscle does not play a causative role in diabetes development (9).
Recent whole-genome sequencing studies show that cancers frequently contain hundreds of putative driver mutations that are suggested to play a causative role in tumour development (Loeb 2011.
