Intravenous opioid, however, has catastrophic side effects like respiratory depression [8].
Any geoengineering scheme powerful enough to eliminate tornadoes would also by definition have catastrophic side effects.
Also, as the thalidomide mess reminded us many years ago, supposedly beneficial medicines can cause catastrophic side effects that may not be recognized until extensive controlled clinical experience has been gained.
Despite such catastrophic side effects, the FDA decided to leave the risk-benefit decision on Xiaflex up to a patient and his doctor.
Would the spleen be able to cope with removing millions of IEs, or could it lead to potentially catastrophic side effects such as splenic rupture?
Marr, who mostly slept through his brushes with death, was oblivious to the dramas of his bedside and the potentially "catastrophic side-effects" of his post-stroke treatment.
Hell and Heaven exist - characters can see them, sometimes - and angels visit the earth with bursts of Holy Presence and catastrophic side-effects.
Steel (2008), building on the work of others (Schlosser and Wagner 2004), therefore attempts to reconstruct this argument as a way of showing that evolved systems are more likely to be modular: systems made of independently manipulable parts can quarantine the effects of changes to specific parts, giving them added flexibility to make local changes without causing catastrophic side-effects.
Even Stubbs has conceded that it would take a "catastrophic collapse" for the Tynecastle side to fail to win the title.
And here I was, year after year, living my theory as the recession dragged on and the month of December became jinxed -- in 2011, Dad passing away as I kept an all-night vigil at his side; in 2012, a catastrophic power spike blowing out one of my $20,000 Mac systems from hard drive to printer (post-warranty).
Mr Guehenno said that in the closed door session he stressed the need for a political process involving both sides to avoid a "catastrophic" civil war.
