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The phrase "a case of speculation" is correct and usable in written English.
It can be used when discussing a situation or scenario that is based on conjecture or uncertain information rather than concrete evidence.
Example: "The report presented a case of speculation regarding the company's future performance, lacking any solid data to support its claims."
Alternatives: "an instance of conjecture" or "a situation of uncertainty".
Similar(59)
The social distribution of migraine has long been a subject of speculation.
Asked about weekend reports of an end to donor anonymity, one health official told Guardian Unlimited: "this is a unfortunate case of premature speculation".
"This is a case based on speculation, guesswork and suspicion of what might have happened," Naftalis said.
The shock of federal agents serving a subpoena on the governor's office, and the scarcity of solid information about the investigation, generated a whirl of speculation about the case in the state capital on Friday.
This was in 1996, and yet the case since then has hovered in a vague limbo of speculation.
There's a lot of speculation.
It set off a frenzy of speculation.
HERE'S a piece of speculation.
Why is a matter of speculation.
Their origins are a matter of speculation.
For now, they share a spotlight of speculation.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com