The phrase "a case of considerable" is correct and usable in written English.
It can be used to describe a situation or instance that is significant or noteworthy in some way.
Example: "This is a case of considerable importance that requires immediate attention from the authorities."
Alternatives: "a matter of significant" or "an instance of substantial".
Telephone Rates In a case of considerable importance in the telecommunications industry, the court agreed over the government's objection to hear a challenge by the GTE Corporation to the rate-setting methodology by which carriers are required to subsidize service at low rates for poorly served areas.
As an adolescent, his curiosity had been noticed by the orator Callistratus, who was then at the height of his reputation, having just won a case of considerable importance.
In case of considerable heterogeneity (I2≥50%) a pooled estimate is not sensible and, therefore, was not calculated [32].
In the case of considerable heterogeneity (I2≥50%), a pooled estimate is not reasonable and, therefore, was not calculated [28].
In case of considerable heterogeneity between study results in a specific comparison that cannot be explained by the defined subgroups, a series of a posteriori (explorative) meta-regression analyses will be performed to identify sources of heterogeneity.
Calcinosis is a relatively common disease manifestation in JDM and occurs in up to 30% of cases; it is a cause of considerable morbidity, and can lead to skin ulceration, pain from nerve entrapment and joint contractures [ 4, 6, 31].
Similar flaws may occur in the case of considerable differences in genetic divergence between the species, particularly if high F values are optimal.
This results in a maximal sample size of 170 BCS that need to be included in the BREATH trial in case of considerable drop-out.
In our next research, we will choose more samples in order to guarantee the sample size in case of considerable non response rates.
In case of considerable heterogeneity between study results that cannot be explained by the a priori defined subgroup and meta-regression analyses, a series of a posteriori (explorative) meta-regression analyses will be performed to identify sources of heterogeneity.
Only in case of considerable increases in ICP or in patients at high risk of nosocomial infections, a moderate elevation of the head of 15° to 30° is recommended, always depending on the CPP [ 34].
