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The emphasis of the Byzantine church on the physical splendour of its edifices was a cardinal factor in determining the characteristics of Russian ecclesiastical architecture.
Here it must be stressed that absence of a heartbeat was never considered a cardinal factor in the determination of death (Bab. Talmud, tractate Yoma 85A).
As we know, in cervical cancer, metastasis through lymphatic vessels is the most common way to spread out and is also a cardinal factor affecting prognosis of patients.
The development of these negative, cynical attitudes and feelings about patients is a cardinal factor in burnout, known as depersonalization [ 27].
Carcinoma of the uterine cervix is one of the most common malignancies in female genital tract in which lymphatic metastasis is the primary route of spread out and a cardinal factor for prognosis of patients.
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Living alone, another factor that has been found to be related to frailty, is related to poorer nutrition, which is a cardinal component of frailty [ 3].
Diabetes is a cardinal risk factor for stroke, affecting 347 million individuals worldwide (6).
DPN is associated with a significant increase in morbidity and represents a cardinal etiologic factor for the development of diabetic foot lesions (1– 3).
The cardinal rule that "you should not invest in any business that you don't understand" should be a key factor that would guide your investment making-decisions.
Over the last 20 years, it has been shown convincingly that the family of colony-stimulating factors (CSF) plays a cardinal role in the early cross-talk between mother and conceptus in both human and animal models (Pollard, 1997; Robertson, 2007).
Alteration in de novo sphingolipid synthesis has emerged as a contributing factor in airway hyperreactivity, a cardinal feature of all asthma types.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com