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Because the residual alteration rate (i.e., minimum dissolution rate) of basaltic glass was considered, the calculated alteration durations represent "upper limits".
Using the values given by CGH-plotter the frequency of copy number changes per tumor was calculated (alterations defined as >3 adjacent clones).
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To further investigate, if detection level of nTARs alters in our two tissue subsets, we calculated the alteration rate between tissues, in case of gene-related nTARs corrected for gene expression changes.
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